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  • Home
  • Step-by-Step
  • LEARN
    • Cord Blood Facts
    • Types of stem cells
    • Diseases Treated >
      • Regenerative Medicine: Cord Blood is Critical
      • Participate in a Cord Blood Clinical Trial
    • Cord Blood FAQs
    • Cord Blood News >
      • RESEARCH
      • PROJECTS and EVENTS
      • RESOURCES
    • Video Gallery
    • Share the Science Archive
    • Find a Cord Blood Bank
  • Get Involved
    • ABOUT US >
      • Scientific Advisory Board
      • Inspiring Partners
    • Register for Newsletter
    • Our Work in Action >
      • World Cord Blood Day
      • Arizona Public Cord Blood Program
      • Share the Science
      • NEXT GENERATION: Cord Blood
      • Cord Blood Conferences & Workshops
      • World Cancer Day
    • Cord Blood Education Champions
    • Internship Program at University of Arizona
    • Start a Cord Blood Donation Program
    • Contact Us
  • DONATE
  • Spanish Version
    • Step-by-Step Spanish
    • APRENDER >
      • Datos de la sangre del cordón
      • Tipos de celdas
    • ENCUENTRE UN BANCO
    • PARTICIPE >
      • COMENZAR UN PROGRAMA DE DONACION
      • Ensayos Clínicos
    • DONAR
    • VIDEOS EN ESPAÑOL
    • NOTICIAS DE LA SANGRE DEL CORDON >
      • Curar la diabetes con sangre del cordón?
      • Ensayos Clinicos sobre el autismo
      • Controversia respecto a las células madre
      • Medicina regenerativa
  • Search

Share the Science: Impact of Temperature on Cord Blood Transplant - Capitano / Broxmeyer

4/1/2022

 
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​Save the Cord Foundation and WellSky are proud to welcome Dr. Maegan Capitano, as our featured speaker for our next edition of Share the Science on Tuesday, April 12th, 2022 2pm ET / 11am PT. Join us to hear Dr. Capitano discuss her latest research published in co-operation with the late Dr. Hal Broxmeyer, focused on the ideal conditions for collecting and processing cord blood for transplant. Recording now available. Register here.

Share the Science is a free webinar series focused on the cord blood industry and the latest research in this field.  As always, we invite both health professionals and the general public to join us for this unique online educational series. Learn more about this exciting educational series here.

How does temperature affect cord blood transplants? It starts at birth.

A special Share the Science, honouring the late Dr. Hal Broxmeyer and his final contributions to cord blood research, led by his colleague and protégé, Dr. Maegan Capitano.
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Dr. Hal Broxmeyer, the Father of Cord Blood
The legacy of Dr. Hal Broxmeyer is felt strongly by his colleagues and the cord blood industry at large. He rightfully earned the title, "Father of Cord Blood."  While his passing in 2021 left us with a true sense of loss, we are forever grateful to him and his colleagues for the innovative work they have done over the years and, in particular, Dr. Broxmeyer's discovery regarding the ability to collect and store cord blood for future use in stem cell transplants, if prepared and frozen promptly after the birth of a child. Given this, it does seem appropriate that one of his last research projects was related to temperature. He and his team sought to answer. . . How does temperature affect the quality of collections and processing of cord blood for stem cell transplants? 

To answer this question and dive deep into this research led by Broxmeyer's lab, we have invited Dr. Maegan Capitano to speak on Share the Science. As the Assistant Professor of Microbiology & Immunology at the Indiana University School of Medicine,  Dr. Capitanto will go in-depth on her latest research undertaken with Dr. Broxmeyer regarding how collecting and processing human cord blood at 4°C within minutes of the baby's birth results in significantly enhanced numbers of rigorously defined phenotypic and functional hematopoietic stem cells.

During this session, Dr. Capitano will discuss a variety of studies from the late Dr. Hal Broxmeyer that show how hematopoietic stem cell numbers collected in cord blood at the birth of a baby is a limiting factor for efficacious use of cord blood in hematopoietic cell transplantation.

We are honoured to have Dr. Capitano join us for this very special edition of Share the Science. Please join us and learn more about this group's amazing work in the world of cord blood.
SHARE THE SCIENCE
with


Maegan L. Capitano, BA, MS, PhD

Assistant Professor of Microbiology & Immunology, ​Indiana University School of Medicine
 
"Impact of Temperature on Cord Blood Transplant Efficacy"

Free webinar.  Open to the public.
​
Tuesday, April 12 at 2 pm ET / 11 am PT

RECORDING NOW AVAILABLE - WATCH HERE
WATCH Now: Dr. Capitano - Impact of Temperature on Cord Blood Transplant Efficacy

About the speaker

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Maegan L. Capitano, BA, MS, PhD

Assistant Professor of Microbiology & Immunology, Indiana University School of Medicine
Associate Member, Indiana University Simon Comprehensive Cancer Center
Member and Hypoxia Core Director, Indiana University NIDDK-designated Cooperative Center of Excellence in Hematology

Maegan L. Capitano earned her B.A. in Biology from St. Mary’s College of Maryland in 2004. During her summers in college, she worked at Memorial Sloan Kettering Cancer Center in the laboratory of Dr. Bo Dupont as a laboratory technician where she developed a passion for research. She next went on to earn a M.S. in Natural Science-Oncology in 2006 and her Ph.D. in Microbiology and Immunology in 2012 at the State University of New York at Buffalo- Roswell Park Cancer Center Division under the mentorship of Dr. Elizabeth Repasky. There she was given the George Meyer’s Award for Proficiency and Academic Excellence in Immunology.

She received her post-doctoral training (2012-2020) and worked as an Assistant Research Professor in the laboratory of Dr. Hal Broxmeyer at Indiana University School of Medicine focusing on Experimental Hematology. In 2021, she joined the faculty of the Department of Microbiology and Immunology at Indiana University School of Medicine as an Assistant Professor. Dr. Capitano’s research focuses on discovering potential new agents that regulate hematopoietic stem and progenitor cell migration, proliferation, differentiation, and survival capacity under normal and stressed conditions. The Capitano lab strives to discover novel methods to 1) improve collection of donor cells for transplant so that the pool of eligible donors is increased and to 2) enhance the efficacy of donor cell engraftment thus shortening the hospitalization/isolation time of patients and subsequently decreasing treatment costs.

We wish to thank Dr. Maegan Capitano for volunteering her time to speak on
Share the Science and sharing her valuable insight
on the efficient collection and processing of cord blood.
​​
We also wish to also thank our generous sponsor and partner for this event,
WellSky Health, who continue to support cord blood
education through our “Share the Science” series.
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Remembering Dr. Hal Broxmeyer, the Father of Cord Blood

12/16/2021

 
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On behalf of the teams at Save the Cord Foundation and the Arizona Public Cord Blood Program, we wish to express our condolences to the family, friends and close colleagues of Dr. Hal Broxmeyer. 

A distinguished professor, a visionary in the medical field, a pioneer who changed the face of medicine through his scientific discoveries realizing the potential of umbilical cord blood stem cells. . . Dr. Hal Broxmeyer has long been regarded as the "Father of Cord Blood."  Importantly, he discovered that cord blood contained life-saving hematopoietic stem and progenitor cells, similar to those found in bone marrow. He work did not stop there. He also confirmed that these cells, collected from something previously regarded as "medical waste," could be frozen for FUTURE use!

These two discoveries opened a whole new avenue of research and ultimately led to the regular use of cord blood stem cells in the treatment of over 80+ life-threatening diseases! His discoveries have literally saved thousands of lives and will continue in the years ahead to save thousands more. In fact, most scientists agree that we are only in the early stages of realizing the true potential of cord blood as research is on-going using cord blood in the emerging fields of regenerative medicine and gene therapy. 

Dr. Broxmeyer, you will be missed. 


To learn more about Dr. Broxmeyer's work, we would encourage you to read the article by Cord Blood Association honoring him, his work and his enormous impact on the medical world.  Read the full article here. . .

Share the Science: Dr. John Wagner - Combatting GvHD with Cord Blood

7/12/2021

 
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Save the Cord Foundation and WellSky are proud to welcome Dr. John Wagner, as our featured speaker for our next edition of Share the Science on July 22nd, 2021 2pm ET / 11am PT. Join us to hear Dr. Wagner discuss his research using umbilical cord blood-derived regulatory T Cells (Tregs) to combat Graft versus Host Disease (GvHD). RECORDING NOW AVAILABLE.
​
Share the Science is a free webinar series focused on the cord blood industry and the latest research in this field.  As always, we invite both health professionals and the general public to join us for this unique online educational series. Learn more about this exciting educational series here.

Preventing GvHD with Regulatory T Cells (Tregs)

Join us to hear pioneering researcher John Wagner, M.D. as he shares some of his latest work involving potential treatment of autoimmunity and graft-versus-host disease (GVHD).

Infection and relapse are the principal obstacles to successful use of allogeneic hematopoietic stem cell transplantation. Prolonged immunodeficiency is a major cause of infection and relapse, particularly in those with high-risk disease, older age, use of in vivo and ex vivo T cell depletion, HLA mismatch, and after the development of acute and chronic GVHD.

Trials have demonstrated that the infusion of umbilical cord blood (UCB) derived regulatory T cells (Tregs) could effectively prevent GVHD. Join Dr. Wagner as he also shares how thymic progenitor cells (Pro-Ts) can repair damaged immune systems, and how UCB can reliably provide large numbers of Pro-Ts suitable for clinical use.
SHARE THE SCIENCE
with

John Wagner, M.D.


Founding Director of the Institute of Cell, Gene and Immunotherapeutics
​at the University of Minnesota

 
"Combatting GVHD with UCB-derived regulatory T cells"

Free webinar.  Open to the public.
​
Thursday, July 22nd at 2 pm ET / 11am PT

RECORDING NOW AVAILABLE
Register Here: Share the Science - Dr. John Wagner - Combatting GvHD with UCB-derived T Cells

About the speaker

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Dr. John Wagner

Founding Director of the Institute of Cell, Gene and Immunotherapeutics at the University of Minnesota


Dr. Wagner's research is focused on the development of novel cell therapies for treatment of life threatening diseases. Examples include the development of regulatory T cells that could be used in the treatment of autoimmunity, organ graft rejection as well as graft-versus-host disease, thymic progenitors to repair damaged immune systems, cardiac myoblasts to reverse heart failure, skeletal myoblasts to repair or replace dystrophic muscle fibers in muscular dystrophy, and expansion of the blood-forming stem cell to speed blood and marrow recovery after high doses of chemotherapy and radiation.

Dr. Wagner is best known for his pioneering work on the use of placental/cord blood as a source of stem cells for transplantation – a procedure that has now been performed in more than 50,000 patients worldwide.

We wish to thank Dr. John Wagner for volunteering his time to speak on
Share the Science and sharing his valuable insight
on the use of cord blood-derived Tcells (Tregs) to combat GvHD.
​​
We also wish to also thank our generous sponsor and partner for this event,
WellSky Health, who continue to support cord blood
education through our “Share the Science” series.
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About Save the Cord Foundation

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Save the Cord Foundation, a 501c3 non-profit organization, was established to promote awareness of the life-saving benefits of cord blood based on u​nbiased and factual information. The Foundation educates parents, health professionals and the general public about the need to preserve this valuable medical resource while providing information on both public cord blood donation programs and private family cord blood banks worldwide. Learn more about our global community.

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