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  • Search
  • Home
  • Step-by-Step
  • LEARN
    • Cord Blood Facts
    • Types of stem cells
    • Diseases Treated >
      • Regenerative Medicine: Cord Blood is Critical
      • Participate in a Cord Blood Clinical Trial
    • Cord Blood FAQs
    • Cord Blood News >
      • RESEARCH
      • PROJECTS and EVENTS
      • RESOURCES
    • Video Gallery
    • Share the Science Archive
    • Find a Cord Blood Bank
  • Get Involved
    • ABOUT US >
      • Scientific Advisory Board
      • Inspiring Partners
    • Register for Newsletter
    • Our Work in Action >
      • World Cord Blood Day
      • Arizona Public Cord Blood Program
      • Share the Science
      • NEXT GENERATION: Cord Blood
      • Cord Blood Conferences & Workshops
      • World Cancer Day
    • Cord Blood Education Champions
    • Internship Program at University of Arizona
    • Start a Cord Blood Donation Program
    • Contact Us
  • DONATE
  • Spanish Version
    • Step-by-Step Spanish
    • APRENDER >
      • Datos de la sangre del cordón
      • Tipos de celdas
    • ENCUENTRE UN BANCO
    • PARTICIPE >
      • COMENZAR UN PROGRAMA DE DONACION
      • Ensayos Clínicos
    • DONAR
    • VIDEOS EN ESPAÑOL
    • NOTICIAS DE LA SANGRE DEL CORDON >
      • Curar la diabetes con sangre del cordón?
      • Ensayos Clinicos sobre el autismo
      • Controversia respecto a las células madre
      • Medicina regenerativa
  • Search

Share the Science: Drs. Malhotra & Zhou - Potential Cord Blood Cell Therapy for Preterm Brain Injury

8/4/2022

 
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​Save the Cord Foundation and WellSky are proud to welcome Dr. Atul Malhotra and Dr. Lindsay Zhou as our featured speakers for the next edition of Share the Science on Wednesday, August 17th, 2022 at 5pm US Eastern Time / 4pm US Central Time. Join us to hear Dr. Malhotra and Dr. Zhou discuss their research on the potential use of cord blood in cell therapy to treat brain injury in preterm infants.

RECORDING NOW AVAILABLE (watch via the Share the Science archive)

​Share the Science is a free webinar series focused on the cord blood industry and the latest research in this field.  As always, we invite both health professionals and the general public to join us for this unique online educational series. Learn more about this exciting educational series here.

Cell Therapy for Brain Injury:
​What does the future hold?

Brain injury continues to be a severe complication as a result of of preterm birth.  In response, prevention and treatment of brain injury in neonates remains a key area of interest for researchers exploring the potential of umbilical cord blood and cord blood-derived cell therapies. In particular, umbilical cord blood-derived cells are being continuously evaluated for their neuroprotective and neuroreparative properties in preclinical and clinical studies. Numerous clinical trials have suggested that cord blood has the potential to reduce apoptosis, inflammatory cytokines and oxidative stress in the brain.

For this edition of Share the Science, we are pleased to welcome both Dr. Atul Malhotra and Dr. Lindsay Zhou from Monash University who will discuss the potential of cord blood in the treatment of brain injury. In particular, they will discuss their own research in this area and a study to test the feasibility of collection and isolation of sufficient UCBCs from cord blood, and the safety of intravenous administration of autologous UCBCs in extremely preterm infants suffering from brain injury during the neonatal period. 

Join us for this fascinating discussion with Dr. Atul Malhotra and Dr. Lindsay Zhou. 
​
SHARE THE SCIENCE
with

Dr. Atul Malhotra & Dr. Lindsay Zhou
Monash Children's Hospital, Department of Paediatrics,
Monash University - Melbourn, Australia

 
"Autologous Umbilical Cord Blood-Derived Cell
Administration in Extreme Preterm Infants" 

Free webinar.  Open to the public.
​
Wednesday, August 17th, 2022  5pm US Eastern Time / 4pm US Central Time
​

RECORDING NOW AVAILABLE
via the Share the Science Archive
Watch NOW via Share the Science Archive:  Cord Blood Cell Therapy for Preterm Brain Injury

About the speakers

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Dr. Atul Malhotra
​
Senior Consultant Neonatologist and Head of the Early Neurodevelopment Clinic at Monash Children's Hospital and Associate Professor (Research) & NHMRC Fellow in the Department of Paediatrics, Monash University.


Associate Professor Atul Malhotra is a Senior Consultant Neonatologist and Head of the Early Neurodevelopment Clinic at Monash Children's Hospital and Associate Professor (Research) & NHMRC Fellow in the Department of Paediatrics, Monash University. He has published over 120 peer-reviewed journal articles, 4 book chapters and his research has attracted over $7.5 million of funding to date. He is also the co-Director of the Newborn Cell Therapies Group at Monash, which has been instrumental in the translation of preclinical therapies from the laboratory to the clinic, including regenerative cell therapies. He led a world-first trial of placental amnion epithelial cells for chronic lung disease of prematurity, and is the Principal Investigator of two cord blood derived cell therapy trials currently recruiting.

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Dr. Lindsay Zhou
​

Consultant Neonatologist at Monash Children's Hospital and a PhD student at the Ritchie Centre and Department of Paediatrics, Monash University.

Dr Lindsay Zhou is a Consultant Neonatologist at Monash Children's Hospital and a PhD student at the Ritchie Centre and Department of Paediatrics, Monash University. Dr. Zhou undertook his paediatric and neonatal training in Melbourne, and also works as a Retrieval Consultant at the Royal Children's Hospital Melbourne. His PhD studies focus on umbilical cord-blood derived cell therapy applications for extremely preterm infants. He is an Associate Investigator on the CordSaFe clinical trial, investigating the safety and feasibility of umbilical cord blood-derived cell collection and administration in infants born at less than 28 weeks.

We wish to thank Dr. Atul Malhotra & Dr. Lindsay Zhou for volunteering their time to speak on
Share the Science and sharing their valuable insight
on the potential of using cord blood in cell therapy to treat preterm brain injury in enfants.
​​
We also wish to also thank our generous sponsor and partner for this event,
WellSky Health, who continue to support cord blood
education through our “Share the Science” series.
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Share the Science: Dr. Mitchell Horwitz - Improved Clinical Outcomes in Cord Blood Transplantation

6/13/2022

 
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Save the Cord Foundation and WellSky are proud to welcome Dr. Mitchell Horwitz, as our featured speaker for our next edition of Share the Science on Wednesday, June 22nd, 2022 1pm ET. Join us to hear Dr. Horwitz discuss the results from his recent research comparing Omidubicel to Standard Myeloablative Umbilical Cord Blood Transplantation.  RECORDING NOW AVAILABLE
​
Share the Science is a free webinar series focused on the cord blood industry and the latest research in this field.  As always, we invite both health professionals and the general public to join us for this unique online educational series. Learn more about this exciting educational series here.

Looking to the future of cord blood transplantation

For over 30 years, cord blood stem cell transplants have been saving lives and bringing new hope to patients fighting over 80 different life-threatening diseases including leukemia, lymphoma and thalassemia. However, despite this impressive track record, transplant doctors are not complacent, but constantly looking for ways to improve on the transplant process whether using cord blood, bone marrow or both.

​In this spirit, Dr. Mitchell Horwitz and his team at Duke University Medical Center have led the way in new and pioneering cord blood research. Recently, the team published their encouraging results from a phase 3 randomized study on the efficacy of omidubicel vs. standards myeloablative umbilical cord blood transplantation. Omidubicel is an ex vivo expanded hematopoietic progenitor cell and non-expanded myeloid and lymphoid cell product that is derived from a single umbilical cord blood unit.

As part of Dr. Horwitz' study, between January 2017 and January 2020, 125 patients ages 13 to 65 years with hematologic malignancies were randomly assigned to this study. Patients received myeloablative conditioning and prophylaxis with a calcineurin inhibitor and mycophenolate mofetil for graft-versus-host disease. 

Join us to learn about the details of this phase 3 study and explore ways that doctors can improve cord blood transplants through innovation.
SHARE THE SCIENCE
with


Mitchell Horwitz, MD
Adult Blood and Marrow Transplant Program and Professor of Medicine at the Duke University Medical Center
 
"Improved Clinical Outcomes with Omidubicel vs. Standard Myeloablative Umbilical Cord Blood Transplantation"

Free webinar.  Open to the public.
​
Wednesday, June 22nd, 2022  1pm ET

RECORDING NOW AVAILABLE in the Share the Science Archive

Register Now for Share the Science with Dr. Mitchell Horwitz

About the speaker

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Mitchell Horwitz, M.D.

​Adult Blood and Marrow Transplant Program and Professor of Medicine at the Duke University Medical Center
​With over 20 years of experience, Dr. Horwitz specializes in allogeneic stem cell transplantation using umbilical cord blood grafts; allogenic stem cell transplantation for Sickle Cell Disease; prevention of acute graft versus host disease through donor stem cell graft manipulation; and improving immune recovery following alternative donor stem cell transplantation using donor graft manipulation or third party thymus transplantation.

We wish to thank Dr. Mitchell Horwitz for volunteering his time to speak on
Share the Science and sharing his valuable insight
on the ways to improve cord blood transplantation.
​​
We also wish to also thank our generous sponsor and partner for this event,
WellSky Health, who continue to support cord blood
education through our “Share the Science” series.
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Share the Science: Impact of Temperature on Cord Blood Transplant - Capitano / Broxmeyer

4/1/2022

 
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​Save the Cord Foundation and WellSky are proud to welcome Dr. Maegan Capitano, as our featured speaker for our next edition of Share the Science on Tuesday, April 12th, 2022 2pm ET / 11am PT. Join us to hear Dr. Capitano discuss her latest research published in co-operation with the late Dr. Hal Broxmeyer, focused on the ideal conditions for collecting and processing cord blood for transplant. Recording now available. Register here.

Share the Science is a free webinar series focused on the cord blood industry and the latest research in this field.  As always, we invite both health professionals and the general public to join us for this unique online educational series. Learn more about this exciting educational series here.

How does temperature affect cord blood transplants? It starts at birth.

A special Share the Science, honouring the late Dr. Hal Broxmeyer and his final contributions to cord blood research, led by his colleague and protégé, Dr. Maegan Capitano.
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Dr. Hal Broxmeyer, the Father of Cord Blood
The legacy of Dr. Hal Broxmeyer is felt strongly by his colleagues and the cord blood industry at large. He rightfully earned the title, "Father of Cord Blood."  While his passing in 2021 left us with a true sense of loss, we are forever grateful to him and his colleagues for the innovative work they have done over the years and, in particular, Dr. Broxmeyer's discovery regarding the ability to collect and store cord blood for future use in stem cell transplants, if prepared and frozen promptly after the birth of a child. Given this, it does seem appropriate that one of his last research projects was related to temperature. He and his team sought to answer. . . How does temperature affect the quality of collections and processing of cord blood for stem cell transplants? 

To answer this question and dive deep into this research led by Broxmeyer's lab, we have invited Dr. Maegan Capitano to speak on Share the Science. As the Assistant Professor of Microbiology & Immunology at the Indiana University School of Medicine,  Dr. Capitanto will go in-depth on her latest research undertaken with Dr. Broxmeyer regarding how collecting and processing human cord blood at 4°C within minutes of the baby's birth results in significantly enhanced numbers of rigorously defined phenotypic and functional hematopoietic stem cells.

During this session, Dr. Capitano will discuss a variety of studies from the late Dr. Hal Broxmeyer that show how hematopoietic stem cell numbers collected in cord blood at the birth of a baby is a limiting factor for efficacious use of cord blood in hematopoietic cell transplantation.

We are honoured to have Dr. Capitano join us for this very special edition of Share the Science. Please join us and learn more about this group's amazing work in the world of cord blood.
SHARE THE SCIENCE
with


Maegan L. Capitano, BA, MS, PhD

Assistant Professor of Microbiology & Immunology, ​Indiana University School of Medicine
 
"Impact of Temperature on Cord Blood Transplant Efficacy"

Free webinar.  Open to the public.
​
Tuesday, April 12 at 2 pm ET / 11 am PT

RECORDING NOW AVAILABLE - WATCH HERE
WATCH Now: Dr. Capitano - Impact of Temperature on Cord Blood Transplant Efficacy

About the speaker

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Maegan L. Capitano, BA, MS, PhD

Assistant Professor of Microbiology & Immunology, Indiana University School of Medicine
Associate Member, Indiana University Simon Comprehensive Cancer Center
Member and Hypoxia Core Director, Indiana University NIDDK-designated Cooperative Center of Excellence in Hematology

Maegan L. Capitano earned her B.A. in Biology from St. Mary’s College of Maryland in 2004. During her summers in college, she worked at Memorial Sloan Kettering Cancer Center in the laboratory of Dr. Bo Dupont as a laboratory technician where she developed a passion for research. She next went on to earn a M.S. in Natural Science-Oncology in 2006 and her Ph.D. in Microbiology and Immunology in 2012 at the State University of New York at Buffalo- Roswell Park Cancer Center Division under the mentorship of Dr. Elizabeth Repasky. There she was given the George Meyer’s Award for Proficiency and Academic Excellence in Immunology.

She received her post-doctoral training (2012-2020) and worked as an Assistant Research Professor in the laboratory of Dr. Hal Broxmeyer at Indiana University School of Medicine focusing on Experimental Hematology. In 2021, she joined the faculty of the Department of Microbiology and Immunology at Indiana University School of Medicine as an Assistant Professor. Dr. Capitano’s research focuses on discovering potential new agents that regulate hematopoietic stem and progenitor cell migration, proliferation, differentiation, and survival capacity under normal and stressed conditions. The Capitano lab strives to discover novel methods to 1) improve collection of donor cells for transplant so that the pool of eligible donors is increased and to 2) enhance the efficacy of donor cell engraftment thus shortening the hospitalization/isolation time of patients and subsequently decreasing treatment costs.

We wish to thank Dr. Maegan Capitano for volunteering her time to speak on
Share the Science and sharing her valuable insight
on the efficient collection and processing of cord blood.
​​
We also wish to also thank our generous sponsor and partner for this event,
WellSky Health, who continue to support cord blood
education through our “Share the Science” series.
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About Save the Cord Foundation

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Save the Cord Foundation, a 501c3 non-profit organization, was established to promote awareness of the life-saving benefits of cord blood based on u​nbiased and factual information. The Foundation educates parents, health professionals and the general public about the need to preserve this valuable medical resource while providing information on both public cord blood donation programs and private family cord blood banks worldwide. Learn more about our global community.

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