Extending Cord Blood to Regenerative Therapies for the Brain - Dr. Joanne Kurtzberg - Share the Science LIVE EVENT
Research exploring the use of cord blood derived therapies is growing and Dr. Joanne Kurtzberg is one of the leading pioneers in this field. Learn about these therapies and the potential use of DUOC-1 as well as the encouraging results of Dr. Kurtzberg's research this October at #ShareTheScience LIVE during the AABB 2018 Annual Meeting. This free special session will be brought to you by Save the Cord Foundation thanks to the generous support of WellSky Health (formerly known as Mediware, Inc.).
Have we crossed into new territory with cord blood?
This year the world celebrates 30 years since the first cord blood transplant was performed. Dr. Joanne Kurtzberg was there. Indeed, Matthew Farrow was her patient. Working together with an international team led by Dr. Eliane Gluckman, the hope was that a cord blood transplant from Matthew's sister would cure him of fanconi anemia. The procedure worked. Thanks to this groundbreaking use of cord blood stem cells, Matthew grew up strong and healthy. Today, he is an adult with his own family. He is living proof that cord blood saves lives. Yet, this milestone procedure opened the door to a multitude of potential uses for cord blood.
Today, cord blood is routinely used to treat more than 80 different life-threatening diseases including many blood cancers. We are also seeing exciting research in the use of cord blood stem cells for regenerative medicine. In particular, researchers are beginning to manipulate cord blood and develop cord blood derived therapies.
Dr. Kurtzberg is one of the best known researchers in this field working primarily with children suffering from various brain injuries. Her studies in children with selective inborn errors of metabolism have shown that cord blood cells, administered intravenously after myeloablative therapy engraft in the brain. DUOC-01, a cord blood derived cellular therapy that promotes myelination, is undergoing testing to augment standard umbilical cord blood treatment in children with leukodystrophies. Dr. Kurtzberg explains that these observations have led us to hypothesize that cord blood cells might also have efficacy treating patients with acquired brain injuries.
Clinical studies to date have been performed to demonstrate safety and efficacy of intravenous infusions of autologous cord blood in babies with hypoxic ischemic encephalopathy, young children with cerebral palsy, congenital hydrocephalus and autism, and adults with acute ischemic stroke. Further development of these therapies using allogeneic cord blood products can provide access to these therapies for all.
On October 15th, we invite you to join us for a special session at the AABB 2018 Annual Meeting where we will host Dr. Kurtzberg for a live Share the Science event. At this event, she will speak about her current research and present the latest results from that work. She will highlight how cord blood banking and transplantation is continuing to evolve. She will also speak about the importance of quality for cord blood units and explain why, if not handled properly, poor quality standards could turn hope into disaster. Attendees will learn the latest in new clinical applications and have an opportunity to participate in a question/answer session with Dr. Kurtzberg.
Extending Cord Blood to Regenerative Therapies for the Brain
Boston Convention Center in room 151 AB | October 15th from 7:00 - 8:15 a.m. ET
Event is RSVP only. Admission is free but seating is limited.
About the speaker
Dr. Joanne Kurtzberg is an internationally renowned expert in pediatric hematology/oncology, pediatric blood and marrow transplant, umbilical cord blood banking and transplant, and novel applications of cord blood in the emerging fields of cellular therapies and regenerative medicine.
Over the last two decades, Dr. Kurtzberg has established an internationally known pediatric transplant program; one of the largest unrelated donor cord blood banks, the Carolinas Cord Blood Bank, in the world; and the Julian Robertson Cell and Translational Therapy Program (CT2) at Duke. Dr. Kurtzberg has published more than 300 peer-reviewed papers, multiple chapters, and scientific reviews. She is a member of the American Society of Hematology, the American Association of Blood and Marrow Transplantation, the American Society of Pediatric Hematology/Oncology, the International Society of Cellular Therapies, the Pediatric Blood and Marrow Transplant Consortium (PBMTC), and other organizations. She serves on the Board of the Foundation of Accreditation of Cellular Therapies, Advisory Council of Blood Stem Cell Transplantation to Health and Human Services. Dr. Kurtzberg was awarded a Lifetime Achievement Award from the PBMTC in 2012.
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We wish to thank Dr. Kurtzberg for volunteering her time to speak on
Share the Science and sharing her valuable insight on cord blood derived therapies.
We also wish to thank our generous sponsor and partner for this event,
WellSky Health (formerly known as Mediware, Inc.), who continue to support cord blood
education through our “Share the Science” series.
Save the Cord Foundation recently interviewed Dr. Charles S. Cox, Jr. about his research using cord blood to potentially treat Traumatic Brain Injury (TBI).
According to Medscape, TBI is defined as, “a non-degenerative, non-congenital insult to the brain from an external mechanical force, possibly leading to a permanent or temporary impairment of cognitive, physical, and psychosocial functions, with an associated diminished or altered state of consciousness.”
Furthermore, traumaticbraininjury.com explains that TBI can limit the use of certain parts of the body and can alter personality. It can impair thinking, movement, sensation, emotional functioning, and more. In addition, no two-brain injuries are the same and the consequences of each individual brain injury may be extremely different.
According to Centers for Disease Control and Prevention, TBI contributes to about 30% of all injury deaths. Every day, 153 people in the United States die from injuries that include TBI.
In this short interview, Dr. Cox gives a brief overview of his work. He and his team recently completed their first acute, autologous cell therapy treatment Phase I study for traumatic brain injury in children aged 5-14. The study represents a significant milestone in Dr. Cox’s research focused on potentially treating traumatic brain injury with cord blood.
View the interview with Dr. Cox below or via our channel on YouTube.
Want to learn more about cord blood clinical trials?
1. Dawodu, ,A (2017) Traumatic Brain Injury (TBI) – Definition, Epidemiology, Pathophysiology. Medscape. Retrieved August 1, 2018, from https://emedicine.medscape.com/article/326510-overview
2. Mayo Foundation for Medical Education and Research, (2018) Traumatic Brain Injury. Mayo Clinic. Retrieved August 1, 2018, from http://www.mayoclinic.org/diseases-conditions/traumatic-brain-injury/symptoms-causes/syc-20378557
3. U.S. Department of Health & Human Services, (2017). TBI: Get the Facts. Centers for Disease Control and Prevention. Retrieved August 1, 2018, from https://www.cdc.gov/traumaticbraininjury/get_the_facts.html
Save the Cord Foundation is proud to be collaborating with the Cord Blood Association and 12 other leading industry groups to launch the first ever Cord Blood Connect conference this September in South Beach, Florida.
The cord blood industry has matured tremendously over the last decade. Yet, it is fair to say that it is still evolving simply because there is so much potential. Over the years, conferences held around the world have been crucial in pushing the industry forward as attendees often learn about new research or improving industry standards. However, it is rare to see a conference truly address all of the major aspects of the cord blood industry specifically. Cord Blood Connect promises to do just that!
Cord Blood Connect is an international conference that embraces all components of the cord blood community – public and private banking, clinical and laboratory investigations, manufacturing, administration, training and education.
Cord Blood Connect
The International Congress for Cord Blood
and Perinatal Tissue Research
September 14-16, 2018
Lowes Miami Beach Hotel
South Beach, Florida, USA
Hosted by the Cord Blood Association, attendees will be given the opportunity over the course of 3 days to explore multiple tracks for clinical and translational science and investigations, as well as education and training for cord blood bank administrative, technical and support personnel.
Cord blood experts from the 12 supporting organziations are leading numerous committees in an effort to identify speakers who will share their expertise and work with attendees during special training sessions. For example, the following committees have been developing the agenda:
Learn more on the Official Website for the conference.
REGISTRATION is now open with discounts for early registration and CBA members.
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