Cord Blood Spotlight at 2017 ISCT Annual Meeting in London

Cord Blood Spotlight at 2017 ISCT Annual Meeting in London

This May, London will welcome the world’s best in the cord blood industry and cellular therapy. Just prior to the 2017 ISCT Annual Meeting, an exclusive 2-day workshop and lecture “Cord Blood Spotlight” will be hosted by FACT, CBA, ISCT, and ASBMT welcoming world-renowned cord blood scientists and transplant physicians.

In the decades since Dr. Eliane Gluckman and her team performed the world’s first cord blood transplant in France, the number of applications for this non-controversial source of stem cells have grown dramatically. Today, cord blood is being used to treat over 80 different diseases.  Since 1988, there have been over 35,000 cord blood transplants worldwide. The industry has grown globally to include a dynamic mix of public, private and hybrid cord blood banks. In particular, research using cord blood for regenerative medicine purposes has continued to evolve in amazing ways. Today, it is not unusual for us to talk about cord blood saving someone from cancer or being used to help a young child with cerebral palsy.

Globally, many of the industry’s players work together helping patients in need crossing public / private barriers as well as international borders. The cord blood industry is unique in that it is not selling a drug but rather enabling parents to help their own families or a stranger in need by storing and processing a valuable, natural medical resource — cord blood. However, while the industry is unique it is not immune to standards. In fact, these standards are even more important given the global nature of the industry and stem cells themselves. Quality assurance is compulsory. Understanding how cord blood is going to be used in the near or distant future is vitally important when considering which processes and standards to apply during the collection and storage process.

The 2-Day “Cord Blood Spotlight” has been designed with these challenges in mind.  The purpose of this meeting is to provide insight on cord blood banking standards and foster a pro-active approach to improving the quality of cord blood banking worldwide. This 2-day event will provide cord blood banks from the globe an opportunity to speak one-on-one with cord blood scientists and transplant physicians to better understand why certain processes are preferred and how banks could potentially increase the number of transplants completed by strengthening quality assurance.

Click here to REGISTER for “Cord Blood Spotlight”

Below is an overview of the 2-day program being proposed by FACT, CBA, ISCT and ASBMT:

cord blood spotlight ISCT London

2017 ISCT Annual Meetings: Cord Blood Spotlight

Click here for more info on the 2017 ISCT Annual Meetings.

Cord Blood World Europe 2017: Educational Approaches

Cord Blood World Europe 2017: Educational Approaches

The Cord Blood World Europe conference in London is just around the corner and Save the Cord Foundation is pleased to announce that we will be participating again this year. Our team will be leading a unique roundtable/workshop called “Educational Approaches” building on themes of collaboration presented by key speakers at this event.

The Cord Blood World Europe conference has evolved over the years into a dynamic platform for collaboration and discussion amongst the cord blood industry’s leading experts. Each year the event welcomes numerous researchers and visionaries from all over the world who have one thing in common. . . cord blood.  Born out of demand from feedback over the years Cord Blood World Europe aims to bring together public and private banks, clinicians, researchers, regulatory bodies and solution providers to tackle the challenges and opportunities facing the industry. The conference focuses on the continued need to increase the number of parents who privately store or donate cord blood, reduce costs, increase utilisation, advance regenerative applications and improve quality.

Cord Blood World Europe 2017
17-18 May 2017
Business Design Center, London
Register Now

In 2017, there will be a special emphasis placed on new collaborations developing in this maturing industry. The conference will serve as a springboard for discussions both publicly and privately on how to move forward globally with research and current cellular therapies using cord blood. In addition to lectures from renowned cord blood pioneers such as Dr. Colleen Delaney of NoHLA Therapeutics/Fred Hutchinson Cancer Center and Dr. Joanne Kurtzberg of Duke University, a series of panel discussions with cord blood experts from both the public and private arenas will allow participants to dig deeper into various topics and seek real world answers to challenges they face as a cord blood bank, a researcher, an oncologist, a charity, etc.

Just to name a few of the presentations/discussions we are looking forward to. . .

  • Keynote presentations from Dr. Colleen Delaney from NoHLA/Fred Hutchinson Cancer Center and Professor Vanderson Rocha of Eurocord
  • Research focused presentations from Dr. Joanne Kurtzberg of Duke University and Dr. Jaap Boelens of UMC Utrecht
  • Panel discussion on “The Advantages of Banking Other Tissue, and the Effect This Will Have on the Cord Blood Industry”
  • Panel discussion on “Cord Blood Expansion: How Close Are We to a Solution for this Bottleneck?”
  • Break out session on “Patient Advocacy” highlighting differences in US and UK mandates
Exclusive Roundtable/Workshop: EDUCATIONAL APPROACHES
Building on themes of collaboration, Save the Cord Foundation will lead a special roundtable/workshop called “Educational Approaches.” This roundtable/workshop will focus on the art of communication and education within the industry. Our team will work with participants in small group sessions to develop educational messages for various audiences. All participants will be given the option to feature their educational messages on our website at Save the Cord Foundation along with a backlink to their website where their teams will be encouraged to build on this message. The goal is to start a series of conversations across the globe, targeting a variety of audiences and building on what is presented at Cord Blood World Europe 2017. PLACES ARE LIMITED.

Please note, places are very limited for the “Educational Approaches” roundtable/workshop with Save the Cord Foundation. Please reserve your spot for the conference and the roundtable via the Terrapin website: http://www.terrapinn.com/conference/cord-blood-world-europe/index.stm

Image courtesy of KROMKRATHOG at FreeDigitalPhotos.net

Mother of Four Won the Battle Against Breast Cancer and Leukemia: Deb Martell, Part 4 #WeCanICan series

Mother of Four Won the Battle Against Breast Cancer and Leukemia: Deb Martell, Part 4 #WeCanICan series

Mother of four, Deb Martell fought breast cancer and won only to discover nine years later that she had developed leukemia (AML). Cord blood saved her life.

Part 4 in our #WeCanICan: Beat Cancer with Cord Blood series, in association with World Cancer Day

Life is so simple. You are born. You go to school. You meet someone nice, get married, have a few kids. . . and boom! Cancer.

Cancer does not discriminate. It can pick on anyone and at any time. Originally from Wisconsin, Deb Martell moved to Denver in 1997 with her family. She was 36 years old at the time and a proud mother of four adorable children aged (4, 6, 9 & 11). Life was moving along nicely and very busy due to the move. So, you can imagine how shocked Deb was when she learned she had breast cancer just two months after the move.

Deb’s doctors moved quickly to put her on a hard course of chemotherapy. They also performed an autologous transplant (using her own stem cells), considered a radical treatment in the late 90’s. The treatment saved her life but also damaged her body severely. In particular, the harsh chemo treatment would prove to have a potentially fatal long-term side effect. Everyone knew there was a risk of this but Deb knew she was facing a life or death choice. She followed her doctor’s advice and won a second chance at life. She won the battle against breast cancer!

Fast forward nine years. . . Deb was enjoying her new life and so grateful to have beaten breast cancer. She and her family had moved again. Now, they were living in Wisconsin. The kids were growing up fast. Her oldest was now 20. The youngest was 13. All were keeping her busy with school runs, getting everyone to afterschool activities like hockey and soccer and volunteering at the church.

This was 2007 and Deb had just returned from dropping her second son off at college. She knew something was wrong. She felt incredibly weak. She made an appointment with her doctor. They drew some blood and realized that she needed two units immediately. A bone marrow biopsy was ordered for the next day. Deb was told that she had been diagnosed with AML (Acute Myeloid Leukaemia). It was serious.

As the testing progressed, her doctor realized that she also had a “Chromosome 7 Abnormality” which most likely developed following the heavy chemotherapy she received back in 1998. The intense chemo treatment had saved her life but forever altered her body.  The fact remained that now she had leukemia and required immediate treatment. The doctor advised her to check into the hospital that same day so that she could start a week of chemo in preparation for a stem cell transplant. They would start looking for a bone marrow donor immediately.

WeCanICan - World Cancer Day - Beat Cancer With Cord Blood - Deb Martell

Deb Martell: Two-time Cancer Survivor – #WeCanICan: Beat Cancer with Cord Blood

Deb immediately thought of her kids, “What? . . . but I can’t. Not today. I have to pick up my kids, make arrangements, I can’t just drop everything and start chemo.” Yes, the realities of motherhood often do not line up with the realities of the medical world. Deb did her best.

She quickly organized the necessary logistics for her children and made calls out to everyone to see if they could be a possible bone marrow donor. Everyone stepped into action. A network of family and friends was set up on Caring Bridge. Deb started chemo that weekend.

Deb’s doctors St. Luke’s Hospital in Milwaukee had hoped that her brother would be a possible match for a bone marrow stem cell transplant. However, the criteria for a bone marrow transplant are strict and sadly he was not a match. Was there another option? Deb was desperate.

A hero emerged. . . Dr. Robert Taylor at St. Luke’s recommended she speak with a colleague of his who was doing exciting work using cord blood to fight cancer. This one conversation would save her life. Deb is grateful to this day that Dr. Taylor truly explored all options. He thought out of the box and put her in touch with Dr. Claudio Brunstein at the University of Minnesota – Fairview Hospital.

Deb met with Dr. Brunstein and the decision was made that a cord blood stem cell transplant would be her best hope for survival. The matching process would be easier than for bone marrow and hopefully they would only need one cord since she was considered a relatively small adult in terms of weight and height. The search began.

Deb proceeded with the chemo treatment and began to prepare her body for the transplant. She started to have numerous adverse reactions and issues with platelet transfusions because of the many antibodies in her system. The Blood Center of Wisconsin did an amazing job of finding the specific HLA matched platelets she needed.

Good news . . . Dr. Brunstein had found a cord blood donation that matched! Not only did it meet the basic criteria for matching, it exceeded it. The cord could have come from anywhere in the world but in Deb’s case it was found in the US which made logistics much easier. That donation turned out to be a 6 to 6 antigen match! Dr. Brunstein and his team also said that it was the largest cord blood collection they had ever seen. That meant that they would not need a second one. One would be enough!

Deb received her cord blood transplant on December 18th, 2007. She ended up staying in the hospital for a total of 36 days and then a local apartment for 3 months during which time she was separated from her family as they continued with school and work. However, her recovery progressed nicely. She did not suffer any problems with Graft versus Host Disease (another benefit of using cord blood instead of bone marrow). Her blood type changed from A+ to O+ and she developed an allergy to cashews. Overall, she made a quick recovery and her doctors were very impressed saying that she was an “exceptional cancer patient.”

Cancer survivor, mother of four, attends family wedding

Post cord blood transplant, Deb Martell attends a family wedding.

This past December, Deb celebrated her 9th birthday. Yes, it has been 9 years and she is cancer free! As you can imagine, Deb takes nothing for granted in life. She wakes up every morning and follows a routine filled with gratitude and healthy choices. “I thank God every morning for my very breath and the blessing it is to live another day. My day starts with prayer and thanksgiving and coffee with coconut oil and raw honey! Followed by my workout (usually),” she says.

Indeed, the experience has taught her and her family to be grateful for so much. Her fight against cancer has also influenced her kids in choices they have made. . . one becoming a lawyer, another a nurse. All of them are intent on making the world a better place. Deb and her family say now that they “don’t look at problems that other people see and give up. We try to learn from those problems.”

Thanks to cord blood, Deb was given another chance at life. Thanks to this valuable medical resource, she has been able to attend graduations, watch her kids blossom, enjoy the outdoors (love this photo of her kayaking!), work part-time . . . she is living and loving life!!

What is Deb’s advice to other cancer patients?

  • Be grateful. Take nothing for granted!
  • Maintain a healthy lifestyle post-treatment. Deb keeps a non-toxic home as much as possible. Her goal every day is to protect and build her immune system. She eats gluten-free, corn-free, non-processed foods, . . . She stays health through choices that she makes daily.
  • One of her favorite rituals which she highly recommends is making a morning smoothie. Deb shared her recipe with us. Looks yummy!
Deb's Smoothie Recipe

1 cup organic spinach

1/2 an avocado

1 heaping T of coconut kefir spread (I get this locally so I’m not sure it’s available everywhere, but use something that has probiotics and live cultures.)

heaping T of LIVfit Superfood Blend or your choice of protein powder

1 small fairly unripe banana

1 cup organic frozen mixed berries

2 tp of cacao powder

8 oz of coconut water or filtered water

1 T of raw honey if you need more sweet

Blend and enjoy!

 

world cancer dayCord blood is an incredible medical resource. Since 1988, there have been more than 35,000 cord blood transplants worldwide.  Far from science-fiction, cord blood is currently used to treat over 80 diseases including sickle cell anemia, lymphoma and leukemia. Cord blood is also proving key for exciting research in regenerative medicine to potentially treating things like autism, spinal cord injury, cerebral palsy, diabetes. . .

Learn more about how cord blood is used to fight cancer by meeting others whose lives have been saved thanks to cord blood.  Discover the full #WeCanICan: Beat Cancer with Cord Blood series (in World Cancer Day).

#WeCanICan : Beat Cancer with Cord Blood – World Cancer Day

#WeCanICan : Beat Cancer with Cord Blood – World Cancer Day

Don’t sit back! Get up and spread the good news! #WeCanICan beat cancer with cord blood!  It is already happening and we are going to celebrate cord blood’s success on World Cancer Day 2017.

Join us to spread the word to parents and medical professionals about this valuable medical resource. Let’s encourage more parents to save the cord. Let’s encourage more hospitals to launch public cord blood donation programs.
Save the Cord Foundation_World Cancer Day

Save the Cord Foundation is a proud participant in World Cancer Day 2017 (visit the WCD site). Of course, cancer awareness and cord blood education go year round but this February 4th everyone is making a special effort to get the word out! Why is this important?  First of all, though doctors have not yet “cured” cancer it is fair to say that huge progress has been made. Part of that progress is largely due to cord blood!

At Save the Cord Foundation, World Cancer Day 2017 will kick off a series of articles and interviews with cancer survivors, the doctors who treat them and, of course, parents who have donated their child’s cord blood. Join us as we reach out to members of the medical community and parents to explain how cord blood is being used to treat 80+ diseases including many blood cancers.

Discover our #WeCanICan: Beat Cancer with Cord Blood series:

Part 1:  Nathan Mumford: Living Proof We Can Beat Cancer with Cord Blood

Part 2:  Diane Paradise: Game Over Hodgkin’s Lymphoma

Part 3:  George Cannette: Stronger Than a Hurricane!

Part 4:  Deb Martell: Mother of Four, Won the Battle Against Breast Cancer and Leukemia

 

 


FACT:  Cord blood is often used to treat things like lymphoma, leukemia and sickle cell anemia.

We support public cord blood donation programs worldwide like Be The Match, State led programs like the Arizona Public Cord Blood Program (US), Hawai’i Cord Blood Bank (US)Jeevan Cord Blood Bank (India), Anthony Nolan (UK), Canadian Blood Services (Canada) . . . the list goes on. But, the key to these programs is having doctors and nurses on board in each hospital.

FACT:  Once thought of as experimental, cord blood transplants have become more and more common. Since the first cord blood transplant was performed on a patient suffering from Fanconi Anemia over 25 years ago there have been more than 35,000 umbilical cord blood transplants in the world. 

There is also an urgency to increase cord blood donations from minority and mixed race families, just like with bone marrow donations.

Current practice in most hospitals is to just throw cord blood away as medical waste when a baby is born.  However, cord blood holds tons of valuable non-controversial stem cells.

FACT:  Collecting cord blood does not hurt the mother or child and can be collected safely in the majority of births.

Our mission is remind doctors, nurses, midwives and parents of these facts. And to remind them that there are people waiting for a donor to treat their cancer. Together, #WeCanICan beat cancer with cord blood. Every action is important on #WorldCancerDay!

Give life twice.  #Savethecord.


 

In addition the materials provided by Save the Cord Foundation, we invite you to discover these tools and facts sheets on cancer awareness, prevention and treatment (source: World Cancer Day & the Union for International Cancer Control) :

ScreenHunter_49 Jan. 29 12.47World Cancer Day: Build a Quality Cancer Workforce (download) 

 

 

 

ScreenHunter_50 Jan. 29 12.50World Cancer Day: Mobilise Networks (download) 

 

 

 

ScreenHunter_51 Jan. 29 12.52

World Cancer Day: Shape Policy Change (download)

 

 

 

ScreenHunter_52 Jan. 29 12.53World Cancer Day: Take Control of My Cancer Journery (download)

 

 

Two Kids Fight Cancer & Cerebral Palsy with Cord Blood (as seen in USA Today)

Two Kids Fight Cancer & Cerebral Palsy with Cord Blood (as seen in USA Today)

dylan praskins cord blood recipient

Being a kid! 6 years after his cord blood transplant, Dylan is having fun.

For USA Today, Save the Cord Foundation was recently asked to speak about treatments using cord blood to treat cancer and cerebral palsy. We took this opportunity to introduce readers to two amazing young boys whose lives have been forever changed thanks to cord blood. Meet Dylan and Ashton.

Read the full article published in a special edition of USA Today, “Expecting Parents.”

Dylan Fought Leukemia and Won

Born in April 2009, Dylan Praskins was diagnosed with infant leukemia or ALL (Acute Lymphocytic Leukemia) at only 8 weeks old. We have followed Dylan’s story since he was diagnosed. Against incredible odds, he won his fight against cancer thanks to cord blood.

Dylan’s case demonstrates why public cord blood donation is so important.

Read more about Dylan here.

Diagnosed with Cerebral Palsy, Ashton Said Good-Bye to his Wheelchair

Viacord Cord blood for cerebral palsy

Ashton was 6 weeks old when he was diagnosed with cerebral palsy. The diagnosis was not expected but luckily, Ashton’s parents had saved his cord blood at birth. At the age of 5, Ashton received his own cord blood stem cells in a simple 20-minute transfusion. Signs of improvement quickly followed.

Learn more about private cord blood banking (or “family banking”).

 

Ashton’s story is not unique. Research using cord blood to treat cerebral palsy, autism, diabetes and more is advancing quickly. As a source of non-controversial stem cells, cord blood is at the forefront of regenerative medicine. Learn more about the science that is helping these two boys have a second chance at life.

Read the full article (as seen in USA Today) to learn more.

 

 

Join the Cord Blood Movement

Public and private cord blood banking are both important. At Save the Cord Foundation, we recognize that every family is different. For some, public banking provides a way for to help others and make use of a valuable resource which would otherwise be thrown away. For others, their family history or personal medical history may mean that private cord blood banking is a priority. Some parents don’t have a public banking option and so choose to privately store their child’s cord blood so that it is not thrown away simply as medical waste.

Regardless of your choice, one thing is clear. Even though cord blood is currently being used to treat over 80 different diseases, we are just starting to understand the potential of this fantastic medical resource. Saving cord blood is the ultimate in recycling. Join the #cordbloodmovement today. Tell a friend about Dylan and Ashton. Encourage them to learn more @SaveTheCord. Empower them with knowledge so that they can make the right choice for them. #SaveTheCord

Click here to get involved and spread the word.

Share the Science: Dr. Charles Cox Jr – Cellular Therapies for Neurological Injuries

Share the Science: Dr. Charles Cox Jr – Cellular Therapies for Neurological Injuries

Save the Cord Foundation and Mediware, Inc. are pleased to welcome Dr. Charles Cox, Jr as a featured speaker on “Share the Science.”  Dr. Cox will be speaking about cellular therapies for neurological injuries, preclinical and early clinical trials occurring in the field, and future outlooks.

Dr. Cox is the George and Cynthia Mitchell Distinguished Chair in Neurosciences and directs the Pediatric Surgical Translational Laboratories and Pediatric Program in Regenerative Medicine at the UTHealth Medical School. He also directs the Pediatric Trauma Program at the UTHealth Medical School/Children’s Memorial Hermann Hospital in the Texas Medical Center.

Recently, Dr. Cox completed the first acute, autologous cell therapy treatment Phase I study for traumatic brain injury in children (aged 5-14) in a collaborative effort between leading institutions in the Texas Medical Center including The University of Texas Medical School at Houston, Memorial Hermann Children’s Hospital, MD Anderson Children’s Cancer Hospital, and The Center for Cell and Gene Therapy (CAGT) at Baylor College of Medicine.  The study has evolved to include analysis of the use of cord blood stem cells in treating traumatic brain injury and the role of heterologous cellular therapies.

It is with great pleasure that we welcome Dr. Cox to “Share the Science” where he will go into great detail about various stem and progenitor cellular therapies as potential treatments for neurological injuries, the differences between these many cell types, preclinical and early clinical trials occurring in the field, and future outlooks.

Dr. Charles Cox, Jr
from the UTHealth Medical School and
Children’s Memorial Hermann Hospital
will present
“Cellular Therapies for Neurological Injuries”
Recorded Friday, February 3rd – 11am Central Time
View the Recorded Webinar: FREE and Open to the Public

View the RECORDED WEBINAR now for SHARE THE SCIENCE with Dr. Charles Cox Jr

As an introduction to this webinar, we recommend viewing the short interview we did with Dr. Cox last year during the Perinatal Stem Cell Conference where he emphasized the role of cord blood in regenerative medicine (read the full article here).

Attendees of this webinar will have the opportunity to learn about:

  • Historical perspective of the development of preclinical data in the field
  • How to differentiate between various cell types
  • Benefits of potential pleiotropic mechanisms of action
  • How to be a better critical reviewer of the literature

Attendees will also be invited to ask Dr. Cox questions live during this event.

 * * * *

We wish to thank Dr. Charles Cox Jr. for volunteering his time to speak on
Share the Science and sharing his valuable insight on cellular therapies for neurological injuries.

We also wish to thank our generous sponsors, Mediware Inc., who continue
to support cord blood education through our “Share the Science” series.

Get Involved. Join the #cordbloodmovement!

Save the Cord Foundation thrives on passionate people like yourself who are eager to share what they have learned about cord blood with others. Whether you are a teacher, parent, doctor, nurse or researcher. . . you can make a difference! Join us on social media and share your favorite article or program from Save the Cord Foundation. Give us a shout when you do and we will let the world know that you are doing your part!

Click here to get involved and spread the word.

Cord blood saves lives. Let’s stop throwing it away. 

VIDEO: Dr. Wise Young, Spinal Cord Injury & Potential Treatments Using Cord Blood

VIDEO: Dr. Wise Young, Spinal Cord Injury & Potential Treatments Using Cord Blood

Together with our sponsor, Mediware Inc., we had the honor of hosting Dr. Wise Young for an exclusive “Share the Science” live presentation during the AABB 2016 annual conference.

Dr. Wise Young’s accolades are many yet what makes him a leading researcher in the cord blood industry is his commitment to bringing treatments to people with spinal cord Injuries.

During the live #ShareTheScience presentation, Dr. Young spoke in great detail about his current research and goals for the future. His presentation led the group to discussing a variety of issues including the fact that cord blood supplies could very quickly be depleted as major medical advances are made using cord blood. Indeed, there is precedent for this if we consider that just a few decades ago cord blood was not used at all and now it is used to treat over 80 different diseases including leukemia, lymphoma, sickle cell and thalassemia.

Many health professionals agree that cord blood holds many distinct advantages.  Learn the facts on cord blood here.

In this short video interview, we asked Dr. Young to speak about briefly about his own groundbreaking research using cord blood to treat spinal cord injury and progress that is being made in the field. He also expanded on the group’s discussion about cord blood supplies, public banking and health care costs for these new therapies. He placed a particular focus on India and third world countries where most families cannot afford treatments or private cord blood banking.  Regarding India, he spoke extensively about the opportunity and challenge which lies before us to make cord blood therapies and storage more accessible in order to fight thalassemia (read a related guest post on India from Jeevan Blood Bank).

The overriding message. . . medicine is advancing fast!  The world needs more cord blood.

 

This interview is meant as a general introduction to Dr. Young’s research and does not go into the same technical depth that his live presentation did. Unfortunately, a recording of the live presentation is not available.

About Dr. Young

Dr. Wise Young, M.D., Ph.D., Distinguished Professor, founding director of the W.M. Keck Center for Collaborative Neuroscience is recognized as one of the world’s outstanding neuroscientists.

Dr. Wise Young built and trained a 25 center clinical trial network in China, Taiwan, and Hong Kong, where human clinical trials using umbilical cord blood mononuclear cells and lithium are underway. In the initial results from the phase II trial in Kunming, China, 75% of the participants (15 out of 20) recovered walking with a rolling walker. He is establishing clinical trial networks in the United States, Norway, and India. Phase IIB trials started in 2015, and phase III trials are getting underway this year.

 

Like this video?

Share it and then join us for our next
Share the Science webinar or live event!

Free and open to the public.

Share the Science: Dr. Colleen Delaney: Applications for Expanded Cord Blood Progenitor Cells

Share the Science: Dr. Colleen Delaney: Applications for Expanded Cord Blood Progenitor Cells

As part of our on-going #SHARETHESCIENCE series, Save the Cord Foundation and Mediware, Inc. are proud to welcome Dr. Colleen Delaney who will speak about the possible clinical applications of expanded cord blood progenitor cells.

As the scientific founder and chief medical officer of Nohla Therapeutics, Inc., Dr. Delaney’s research interests focus on the role of the Notch signaling pathway in hematopoietic stem cell regulation and ex-vivo expansion of umbilical cord blood stem and progenitor cells for clinical applications.

The success of her research led to the establishment of Nohla which is a cellular therapy company focused on developing off-the-shelf, universal donor therapies that require no HLA matching. Her group has developed a novel and clinically feasible method for the ex vivo expansion of cord blood derived hematopoietic stem and progenitor cells in the presence of Notch ligands. This work was translated into a novel pilot study investigating the use of ex vivo expanded cord blood progenitors to augment conventional cord blood transplantation.

She has since extended this work to investigate the potential of cryopreserved, non-HLA matched “off-the-shelf” ex vivo expanded cord blood progenitor cells to provide rapid but transient myeloid reconstitution in the setting of cord blood transplant and following dose-intensive chemotherapy.

For this Share the Science webinar, Dr. Delaney discusses methods for expanding cord blood stem and progenitor cells, and the clinical application of these cells for cord blood transplant and chemotherapy-induced neutropenia.

Dr. Colleen Delaney from NoHLA Therapeutics
presents
“Clinical Applications for Expanded Cord Blood Progenitor Cells”
RECORDED:  Wednesday, December 14th: Noon – 1 p.m. central time
Webinar:  Free to register. Open to the public.

VIEW this recorded SHARE THE SCIENCE webinar featuring Dr. Colleen Delaney: Clinical Applications of Expanded Cord Blood Progenitor Cells

Cord blood is an effective and widely used source of stem cells for patients undergoing hematopoietic stem cell transplant for hematologic malignancies. While cord blood offers some distinct advantages over conventional stem cell sources, delayed engraftment due to the low cell dose available in each unit continues to be a challenge in the transplant setting. This webinar will cover development and clinical translation of methodologies for the ex vivo expansion of cord blood stem and progenitor cells.

Dr. Delaney will also discuss the clinical use of expanded cord blood progenitors, which has been shown to be safe in the settings of hematopoietic transplant and dose-intensive chemotherapy. In the cord blood transplant setting, use of these expanded cells has been shown to reduce time to neutrophil and platelet recovery as well as being associated with less severe acute GVHD. In the setting of chemotherapy-induced neutropenia, expanded cells have been shown to decrease the rate of documented infection.

  *  *  *

We wish to thank Dr. Delaney for volunteering her time to speak on Share the Science and sharing her valuable insight on cord blood.

We also wish to thank our generous sponsors, Mediware Inc., who continue to support cord blood education through our “Share the Science” series.

Discover the full Share the Science series and view archived webinars highlighting the latest cord blood research.

powerhouses of science - cord blood research

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About Save the Cord Foundation

Save the Cord Foundation, a 501c3 non-profit organization, was established to promote awareness of the life-saving benefits of cord blood based on unbiased and factual information. The Foundation educates parents, health professionals and the general public about the need to preserve this valuable medical resource while providing information on both public cord blood donation programs and family cord blood banks worldwide.

Support Save the Cord Foundation

Our mission depends on supporters like you. Please support our cause by making a donation or promoting our website and message where you can. We appreciate all the support!
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