Share the Science LIVE with Dr. Joanne Kurtzberg: Cord Blood for Autism, Cerebral Palsy and more

Share the Science LIVE with Dr. Joanne Kurtzberg: Cord Blood for Autism, Cerebral Palsy and more

EXCLUSIVE LIVE EVENT:
Join us for a special edition of Share the Science featuring Dr. Joanne Kurtzberg at this year’s AABB Annual Meeting in San Diego, California.

Update: This presentation was made live on October 9th, 2017 during the AABB 2017 Annual Meetings. For more information, please contact Save the Cord Foundation.

Dr. Joanne Kurtzberg is recognized around the world for her outstanding work in cord blood research. In recent years, her research has been focused on using cord blood to potentially treat autism in young children. As the results from her clinical trials have started to come in, the medical world and parents have taken notice.  She was recently interviewed by CNN along with her colleague, Dr. Geraldine Dawson, Director of Duke’s Center for Autism and Brain Development, about the encouraging results from these clinical trials.  With more than two-thirds of children showing improvement, Dr. Kurtzberg and her team are now moving into phase two hoping to find a long-term treatment option for children with autism.

According to Dr. Kurtzberg, cord blood cells can work through paracrine and trophic mechanisms to help endogenous cells heal brain tissue damaged by disease or injury. Learning from observations made using unrelated donor umbilical cord blood transplant after myeloablative chemotherapy to treat children with certain inherited metabolic diseases, cord blood therapies have been developed to treat children with acquired brain injuries, like hypoxic ischemic encephalopathy, cerebral palsy, and autism.

As the research moves forward and new clinical trials begin, Dr. Kurtzberg has agreed to speak with our Share the Science community about the safety and feasibility of using autologous cord blood infusion in young children with autism spectrum disorder. She will also expand her talk into other areas of possible clinical application for cord blood therapies.  Join us for this exclusive live event at the AABB Annual Meetings in San Diego, California.

Share the Science LIVE at AABB
Dr. Joanne Kurtzberg
“Novel applications of cord blood derived therapies
for genetic and acquired brain diseases.”

San Diego Convention Center: Room 29B
San Diego, CA | MONDAY, OCTOBER 9, 2017| 7 a.m. – 8:15 a.m. PACIFIC TIME
Free to register. Open to all.

REGISTER HERE for SHARE THE SCIENCE (Live at AABB 2017): Dr. Joanne Kurtzberg, “Novel applications of cord blood derived therapies for genetic and acquired brain diseases” *NOTE: Attendance is limited and access to the event will be granted to the first 100 people to register.

 

Data from early phase human clinical trials for safety and efficacy in these diseases will be presented by Dr. Kurtzberg. Results of preclinical and IND-enabling studies will be presented to provide information about safety and potential mechanisms of action of cord blood cells in this setting.

In addition, attendees will learn about:

  • The history and evolution of cord blood banking and transplant
  • About quality measures of cord blood units
  • About new clinical applications for cord blood therapies

About the speaker

Joanne Kurtzberg, MD is the Director, Pediatric Blood and Marrow Transplant Program, Chief Scientific and Medical Officer, Robertson Clinical and Translational Cell Therapy Program, Director, Carolinas Cord Blood Bank and Co-Director, Stem Cell Laboratory.

She is an internationally renowned expert in pediatric hematology/oncology, pediatric blood and marrow transplant, umbilical cord blood banking and transplant, and novel applications of cord blood in the emerging fields of cellular therapies and regenerative medicine.

Over the last two decades, Dr. Kurtzberg has established an internationally known pediatric transplant program; one of the largest unrelated donor cord blood banks, the Carolinas Cord Blood Bank, in the world; and the Julian Robertson Cell and Translational Therapy Program (CT2) at Duke.

Dr. Kurtzberg has published more than 300 peer-reviewed papers, multiple chapters, and scientific reviews. She is a member of the American Society of Hematology, the American Association of Blood and Marrow Transplantation, the American Society of Pediatric Hematology/Oncology, the International Society of Cellular Therapies, the Pediatric Blood and Marrow Transplant Consortium (PBMTC), and other organizations. She serves on the Board of the Foundation of Accreditation of Cellular Therapies, Advisory Council of Blood Stem Cell Transplantation to Health and Human Services. Dr. Kurtzberg was awarded a Lifetime Achievement Award from the PBMTC in 2012.

 

We wish to thank Dr. Kurtzberg for sharing her
valuable insight on cord blood research for autism
with our Share the Science community.
We also wish to thank Mediware, Inc.
for their generous support making this webinar possible. 

Share the Science continues to be a popular series within the cord blood community and beyond. We welcome your input on the series and suggestions for future speakers. Give your feedback here.

powerhouses of science - cord blood research
Previous Share the Science presentations have been archived for your reference. Discover the work of leading scientists and cord blood industry experts through this educational series. View the archive now.

Share the Science is made possible thanks to the generous support of Mediware, Inc.

 

Share the Science: Dr. Kevin Burns, Treating Acute Kidney Injury

Share the Science: Dr. Kevin Burns, Treating Acute Kidney Injury

 

RECORDING COMING SOON:  Acute kidney injury (AKI) is incredibly common, affecting as many as 20% of hospitalized patients according to the National Kidney Foundation.  Sadly, despite years of research, doctors have not found an effective treatment for acute kidney injury. As a result, mortality rates remain high at 1-5% of hospitalized patients. However, the research of Dr. Kevin D. Burns from the Ottawa Hospital Research Institute is providing new hope for patients and cord blood may be the key.

Save the Cord Foundation and Mediware, Inc. are proud to welcome Dr. Kevin Burns to speak about his research on the next edition of our popular webinar series, Share the Science (learn more about the series here). A professor of medicine in the division of Nephrology at the Department of Medicine of the Ottawa Hospital and University of Ottawa, Dr. Burns has dedicated his career to kidney research.

Using cord blood for acute kidney injury

Image courtesy of yodiyim at FreeDigitalPhotos.net

Dr. Burns will present research findings from his laboratory on the reparation properties of extracellular vesicles (exosomes) isolated from human cord blood-derived endothelial colony forming cells (ECFCs) in experimental Acute Kidney Injury. When infused into mice with ischemia/reperfusion Acute Kidney Injury, ECFC exosomes protect against loss of kidney function, prevent inflammatory cell infiltration into the kidneys, and inhibit apoptotic responses. Using next-generation sequencing of small RNAs, his lab found that ECFC exosomes are highly enriched in microRNA-486-5p, which targets the pro-apoptotic factor PTEN. Data from his lab supports the notion that infused exosomes transfer microRNA-486-5p to injured kidney endothelial cells after ischemia/reperfusion Acute Kidney Injury, leading to inhibition of PTEN and subsequent activation of the pro-survival Akt pathway. Finally, he will present data indicating that infused ECFC exosomes selectively home to the injured kidneys after Acute Kidney Injury. This webinar will present information suggesting that ECFC-derived exosomes hold promise as potential therapeutic agents in humans with Acute Kidney Injury.

Join us for this presentation. . .

Share the Science with Dr. Kevin D. Burns
“Cord Blood Endothelial Colony Forming Cell-Derived Exosomes in Acute Kidney Injury”
Wednesday, September 20, 2017 at 3-4pm Central Time
Free to register. Open to the public.

REGISTER HERE for SHARE THE SCIENCE: Dr. Kevin Burns, “Cord Blood Endothelial Colony Forming Cell-Derived Exosomes in Acute Kidney Injury”

 

Recommended reading: https://www.ncbi.nlm.nih.gov/pubmed/26073035

During the webinar, attendees will learn about:

  • Clinical significance of acute kidney injury and the rationale for the use of cellular therapy
  • Effects of administration of ECFCs in experimental ischemia/reperfusion Acute Kidney Injury
  • Potential role of ECFC-derived exosomes in mediating therapeutic responses in Acute Kidney Injury in vivo and in cell culture models
  • Potential role of microRNA transfer in the kidney in mediating the protective effects of exosome treatment

About Kevin D. Burns MD, CM, FRCP(C):

Dr. Burns is a professor of medicine in the division of Nephrology at the Department of Medicine of the Ottawa Hospital and University of Ottawa. He is senior scientist and director of the Kidney Research Centre of the Ottawa Hospital Research Institute and is cross-appointed to the Department of Cellular and Molecular Medicine. Dr. Burns’ research has focused on the function and regulation of the intrarenal renin-angiotensin system in diabetic nephropathy and hypertension and the pathogenesis and treatment of acute kidney injury.

He received his BSc and MD degrees from McGill University and completed internal medicine residency and clinical nephrology fellowship training at the University of Ottawa. Dr. Burns also undertook basic science research training at Vanderbilt University Medical Center. His laboratory has been supported by funds from the Canadian Institutes of Health Research, the Kidney Foundation of Canada, and the Canada Foundation for Innovation/Ontario Innovation Trust.

Dr. Burns is past president of the Canadian Society of Nephrology and is chair of the steering committee for the KRESCENT Program, a national kidney research training program launched by the Canadian Society of Nephrology, the Kidney Foundation of Canada, and the Canada foundation for Innovation/Ontario Innovation Trust. In 2010, Dr. Burns received the Medal for Research Excellence from the Kidney Foundation of Canada in recognition of his contributions to kidney research in Canada. To learn more about the KRESCENT program, please click here. 

______________________

We wish to thank Dr. Kevin Burns for sharing his
valuable insight on cord blood and kidney research
with our Share the Science community.
We also wish to thank Mediware, Inc.
for their generous support making this webinar possible. 

Share the Science continues to be a popular series within the cord blood community and beyond. We welcome your input on the series and suggestions for future speakers. Give your feedback here.

powerhouses of science - cord blood research
Previous Share the Science presentations have been archived for your reference. Discover the work of leading scientists and cord blood industry experts through this educational series. View the archive now.

Share the Science is made possible thanks to the generous support of Mediware, Inc.

 

About Save the Cord Foundation

Save the Cord Foundation, a 501c3 non-profit organization, was established to promote awareness of the life-saving benefits of cord blood based on unbiased and factual information. The Foundation educates parents, health professionals and the general public about the need to preserve this valuable medical resource while providing information on both public cord blood donation programs and family cord blood banks worldwide.

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